球王会

李 磊

發布者:衛生檢驗學系發布時間:2017-07-18瀏覽次數:2456


李磊,男,工學博士,教授,博士研究生導師,南京醫科大學衛生檢驗與檢疫學系主任,全球健康中心PI2000年獲南昌大學食品科學博士學位,曾在廈門大學、香港浸會大學進行分析化學博士后研究工作。現主要從事衛生檢驗檢疫新原理與新技術、衛生檢驗檢疫與疾病防控、食品與環境健康因素分析與風險評價教學和研究。曾主持國家高科技發展研究863計劃、國家自然科學基金、科技部和環保部科技專項等課題,研究成果發表在GUTACS Applied Materials & InterfacesElectrochimica ActaEnvironmental ResearchJournal of Functional FoodsNutrientsRSC advancesSCI收錄期刊上,獲國家發明專利和實用新型專利5項。主編國家衛健委衛生檢驗與檢疫專業規劃教材《儀器分析》、《衛生化學實驗》、《衛生微生物學》(數字融合教材)等教材,副主編《中華醫學百科全書·衛生檢驗學》等專著。曾獲國家高等教育教學成果二等獎、江蘇省高等教育教學成果一、二等獎等。

 

研究方向

1. 衛生復雜體系檢驗與檢疫新原理及新技術

2. 食品與環境健康因素分析與評價

3. 衛生檢驗檢疫與疾病防控

 

聯系方式

地址:南京市江寧區龍眠大道101南京醫科大學志誠樓118

電話:025-86868404

郵箱:lilei@njmu.edu.cn; drleili@hotmail.com

 

 

主要在研項目

1. 主持國家自然科學基金基于FCM/FACS-GC/UPLC-MS/MS聯用解析特定腸道菌預防結直腸癌作用及機制”  81973096)。

2. 主持國家自然科學基金金屬化學形態納米識別-FI-HPLC/GC-ICP-MS聯用分析及代謝組學研究81673228)。

 

近期代表性論文(通訊作者*):

1. Lijuan Wang#, Lei Tang#, Yiming Feng#, Suying Zhao, Mei Han, Chuan Zhang, Gehui Yuan, Jun Zhu, Shuyuan Cao, Qian Wu, Lei Li*, Zhan Zhang*. A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8+ T cells in mice. Gut, 2020, 3, doi: 10.1136/gutjnl-2019-320105.

2. Jiayong Dai#, Le Yao#, Xingsu Gao, Shumeng Bai, Xian Chen, Lei Li*, Jibin Song*, Huanghao Yang. To achieve ultrasensitive electrochemical detection of mercury ions employing metallic 1T-MoS2 nanosheets. Electrochimica Acta, 2020, 355C: 136800. https://doi.org/10.1016/j.electacta.2020.136800

3. Jun Zhu#, Lei Tang#, Shanlei Qiao, Lijuan Wang, Yiming Feng, Li Wang, Qian Wu, Ping Ding, Zhan Zhang*, Lei Li*. Low-dose methylmercury exposure impairs the locomotor activity of zebrafish: role of intestinal inositol metabolism. Environmental Research, 2020,190110020. https://doi.org/10.1016/j.envres.2020.110020

4. Jiayong Dai, Jibin Song, Yuan Qiu, Jingjing Wei, Zhongzhu Hong,Lei Li*, Huanghao Yang*. Gold Nanoparticle-Decorated g?C3N4 Nanosheets for Controlled Generation of Reactive Oxygen Species upon 670 nm Laser Illumination. ACS Applied Materials & Interfaces, 2019, 11, 10589-10596.

5. Yongxin Qiu#, Wenqi Shan#, Ye Yang#, Ming Jin#, Yi Dai#, Hanyu Yang, Ruonan Jiao, Yunwei Xia, Qinqiang Liu , Liang Ju , Guangming Huang, Jianping Zhang, Lihua Yang*, Lei Li*, Yuan Li*. Reversal of sorafenib resistance in hepatocellular carcinoma: epigenetically regulated disruption of 14-3-3η/hypoxiainducible factor-1α. Cell Death Discovery, 2019, 5: 120. https://doi.org/10.1038/s41420-019-0200-8

6. Jun Zhu#, Chundan Wang#, Xingsu Gao, Jiansheng Zhu, Li Wang, Shuyuan Cao, Qian Wu, Shanlei Qiao*, Zhan Zhang*, Lei Li*. Comparative effects of mercury chloride and methylmercury exposure on early neurodevelopment in zebrafish larvae. RSC Advances, 2019, 910766-10755.

7. Xinyue Wu#, Lijuan Wang#, Lei Tang, Li Wang, Shuyuan Cao, Qian Wu, Zhan Zhang*, Lei Li*. Salvianolic acid B alters the gut microbiota and mitigates colitis severity and associated inflammation. Journal of Functional Foods, 2018, 46: 312-319.

8. Suying Zhao#, Shuyuan Cao#, Lan Luo, Zhan Zhang, Gehui Yuan, Yanan Zhang,Yanting Yang, Weihui Guo, Li Wang, Feng Chen, Qian Wu*, Lei Li*. A preliminary investigation of metal element profiles in the serum of patients with bloodstream infections using inductively-coupled plasma mass spectrometry (ICP-MS). Clin Chim Acta, 2018, 485: 323-332.

9. Xingsu Gao#, Jiayong Dai#, Hongyan Zhao#, Jun Zhu, Lan Luo, Rui Zhang, Zhan Zhang*, Lei Li*. Synthesis of MoS2 nanosheets for mercury speciation analysis by HPLC-UV-HG-AFS. RSC Advances, 2018, 8, 18364-18371.

10. Zhan Zhang, Xinyue Wu, Shuyuan Cao, Meghan Cromie, Yonghua Shen, Yiming Feng, Hui Yang, Lei Li*. Chlorogenic Acid Ameliorates Experimental Colitis by Promoting Growth of Akkermansia in Mice. Nutrients, 2017, 9(7): 677


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