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???3??????????????o?????????????????????????Molecular Oncology?????????????????o???

????????????????????????????????????'???2020-11-13????????????556

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?o?????????????????????????Molecular Oncology?????????????????o???

  

????????????????3?????????????????o????????????????????Epigenetic-smoking interaction reveals histologically heterogeneous effects ofTRIM27DNA methylation on overall survival among early-stage NSCLC patients??????????????(Research Article)????????????????????????????????????????????????????(Discovery-driven Translational Cancer Research)?-|?????????Molecular Oncology(IF = 6.574)????1????'????o????????2020?1'14??11??????????????o??????

  

  

??????????o??????|???????????o?o???????o3????????????????????????????????????????????????-|??????????-|?-?????????????????????-???????'???????1?????????-?????????????'?????-?????????'?????????????-??1????????????????????27 (TRIM27)???o???????????-??????????????????????????????????????????????????????????????o??????????-????????|??????????????????????|TRIM27??o????????????????????????o?????o???DNA??2??o????'?13???????????????????o??????????????????????-|??3???????o?o????????????????????oo????3??????????????????o???????-????????cg05293407??????????o3???????????????????3????????????????-|????1???????????1???????o?????????????o????oo????-?????????????'?????????o?o????oo????????????o3?????oo?????????????o?o|???????cg05293407-???????o?o??????????????????o????'????????????????????????????????o?o????2?????2???????????o????????????????????????-?????????

?????2019??????????????-|????????????????????????????????2019?o?????????????????????????o?o?????????????????????????????????????3????????????-????????????????o?o???????????????????????3?????????????????-|????????????-|??David C. Christiani????????o?o??????????????

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???????????????-|?3??????????????????????????2003?1'???????????3??????????o?????????????????????2????-|?????????????????????????????????????????-?o????o??1'??????????o?????-|?-|??????2012?1'??????????-??????????o?????????-|?????????????1'????????????????30????|??3???????????????1'??????????o?????-|?-|?????????????1'????????????????o?-|??????????????????????o???????1???'?'?????????????????o?????????oo??????

   

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????'???2020?1'11???

?????????Molecular Oncology

????????Epigenetic-smoking interaction reveals histologically heterogeneous effects ofTRIM27DNA methylation on overall survival among early-stage NSCLC patients

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